Prescription drug commercials on TV, where we are urged to ask our doctors for medications to treat arthritis, gout,diabetes, ED (erectile dysfunction), COPD (chronic obstructive pulmonary disease), depression, and anything else, are impossible to avoid.
And although the ads always close mentioning a list of the possible really serious adverse reactions such as heart attacks, strokes, cancer or even death, which they can cause, it seems as if we have become utterly desensitized to such warnings because we keep asking for and taking more and more of them without even questioning why our society is getting sicker than ever before, why we have been transformed into chronic patients and no one is ever cured of his/her own disease by these medicines.
One of the main reasons for our poor health is that our health system focuses on prescription medications that do not treat the underlying cause of illness.
A Shocking Truth
Nearly all prescription medications are formulated to work by poisoning enzymes and blocking receptors in our body (to poison us!!!) So they really do not cause side effects, THAT’S JUST THE WAY THEY ARE DESIGNED.
Does it make sense to voluntarily put these poisons into your body??
So l invite you all to read again through this list of the damages and ravages that prescription medicines can cause to us and
think if you really want to keep taking them or you should look for an alternative healing source.
The anti-depressant Cymbalta (duloxetine) can cause a host of side effects. Cymbalta was originally approved by the FDA in 2004 for the treatment of major depression. It is officially an SNRI (serotonin-norepinehprine reuptake inhibitor) -type antidepressant. and is somewhat similar to other antidepressants such as EFFEXOR (venlafaxine) and PRISTIQ (desvenlafaxine). And in 2010 the FDA also approved it to treat musculoskeletal pain associated with arthritis and lower back pain in 2010.
Lilly, the drug company that makes Cymbalta, has been aggressively marketing it as a good way to deal with chronic low back pain and osteoarthritis.
Cymbalta (Duloxetine) Side Effects
- Nausea, stomach pain, constipation, diarrhea, decreased appetite, vomiting
- Dry mouth
- Insomnia, anxiety, tremor
- Dizziness, fatigue, sleepiness
- Sweating, hot flashes
- Blurred vision
- Sexual dysfunction, lowered libido, erection difficulties, lack of orgasm
- Liver damage
- Serious skin reactions, rash, hives (requires immediate MD assistance!)
- Irregular heart rhythms
- Bleeding problems
- Blood pressure problems
- Interaction with other drugs (leading to serotonin syndrome among other reactions)
- Depressed mood, suicidal thoughts and behavior, suicide
There is another problem with Cymbalta: when people try to stop taking the drug, they frequently report unpleasant withdrawal symptoms like:
- Brain “Zaps” (electric shock-like sensations in the brain)
- Dizziness, light-headedness, vertigo, feeling faint
- Anxiety, irritability, hostility
- Nausea, diarrhea, digestive upset
- Tremor, hands shaking, nerve tingles, strange sensations
- Fatigue, tiredness, lack of energy
- Visual disturbances
- More Frequent Attacks of Cataplexy that can cause collapsing on the floor.
- Triggering of Cataplexy (a sudden loss of muscle tone brought on by strong emotion, such as fear, anger or excitement)
BETA BLOCKERS (ATENOLOL, METOPROLOL PROPRANOLOL)
Beta blockers have been prescribed as a primary treatment for high blood pressure (Hypetension) by american physician for decades. Millions of prescriptions are dispensed for such medications annually.
Beta blockers such as ATENOLOL, BISOPROLOL, LABETALOL, METOPROLOL, NADADOL and PROPANOLOL, have been used also for decades to treat irregular heart rhythms, angina and even migraine headaches.
New guidelines for the treatment of hypertension with betablockers, published in the Journal of the American Medical Association (JAMA, Dec. 18, 2013) have placed them to the back of the line because there’s evidence that their their effectiveness in treating high blood pressure has been disappointing and there is even suggestion of harm.
According to Franz Messerli, MD, one of the country’s most renowned hypertension expert, wrote an article titled “Beta-Blockers in Hypertension–The Emperor Has No Clothes.” Here was his conclusion:
“We systematically analyzed all available outcome studies and found no evidence that beta-blocker based therapy, despite lowering blood pressure, reduced the risk of heart attacks or strokes. Despite the inefficacy of beta-blockers, the incidence of adverse effects is substantial. In the MRC [Medical Research Council] study, for every heart attack or stroke prevented, three patients withdrew from atenolol because of impotence, and another seven withdrew because of fatigue. Thus the risk/benefit ratio of beta-blockers is characterized by lack of efficacy and multiple adverse effects.” F. H. Messerli et al., American Journal of Hypertension
A study was published in the Journal of the American Medical Association (JAMA, Oct. 3, 2012) showed no benefit from beta blockers in high-risk heart patients At the end of the study, where over 44,000 people were followed for almost four years, there was no evidence that beta blockers prevented second heart attacks, strokes or death due to cardiovascular causes.
Beta Blocker Side Effects:
- Fatigue, tiredness, depression drowsiness
- Dizziness, lightheadedness, vertigo
- Itchy skin rash
- Difficulty breathing, asthma, wheezing
- Slow heart rate, palpitations
- Cold hands or feet , Raynaud’s syndrome, peripheral edema (swelling)
- Sensitivity to sunlight, sunburn
- Heart block (a problem with the rhythm)
- Blood disorders
- Memory problems, confusion
- Nightmares, insomnia, anxiety
- Digestive upset, diarrhea, nausea, constipation, flatulence
- Arthritis, joint pain
BUT Beta blockers cannot be stopped suddenly. Side effect of sudden stop are:
- chest pain,
- irregular heart rhythms
- heart attack
RECLAST and other bisphosphonates, alendronate (FOSAMAX), ibandronate (BONIVA) or risedronate (ACTONEL)
People taking bisphosphonates like are at increased risk for broken thigh bones (atypical femur fractures).
Your bones are in a continuous state of modification. this remodeling process constantly breaks down old bone and rebuilds new bone. The hypothesis for what causes of fractures is that bisphosphonates “freeze” the bones in an unnatural way. They look stronger on bone mineral density tests, but micro-cracks may form that make the bones more fragile and susceptible to stress fractures.
Other Reclast Side Effects:
Atypical femur fractures are not the only Reclast side effects to be aware of. Here are some other complications people need to know about:
- Arthritis pain
- Muscle pain
- Pain in an arms, shoulder, back or legs
- Bone pain
- Fever, chills, fatigue, lethargy, flu-like symptoms
- Nausea, vomiting, indigestion, stomach pain, loss of appetite
- Heart palpitations or arrhythmias,
- Kidney damage
- Jaw bone death (osteonecrosis of the jaw)
- Eye irritation, eye damage
An anti-arrhythmic medication that comes with a long list of serious side effects. This is especially true of amiodarone (Cordarone, Nexterone, Pacerone), a drug used to treat arrhythmias approved by the FDA in 1985.
The feds caution clearly that
- the drug has life-threatening side effects and
- it is a difficult drug to manage.
- it that should be prescribed only for life-threatening irregular rhythms of the ventricles (“recurrent ventricular fibrillation” or “recurrent hemodynamically unstable ventricular tachycardia”) only when other treatments have failed.
- that patients should only be started on amiodarone in a hospital setting to reduce the likelihood of a life-threatening complication.
Amiodarone Side Effects:
- Lung toxicity is common and can be fatal; symptoms may include wheezing, difficulty breathing, fever, shortness of breath and coughing up blood. Pulmonary fibrosis is a very serious complication of amiodarone therapy.
- Liver damage, liver enzyme elevation, hepatitis
- Worsening of irregular heart rhythms, slow heart rate
- Thyroid disorders, hyperthyroidism, hypothyroidism, thyrotoxicosis
- Serious visual disturbances, loss of vision, optic nerve damage, blindness
- Dangerous or deadly drug interactions; it can interact with many other medications in very dangerous ways. Never combine amiodarone with any other drugs without having the prescriber and pharmacist double check for incompatibility reactions.
- Fatigue, tiredness, unsteadiness, dizziness
- Tremor, hand shaking
- Nerve tingling in extremities, burning or pain in fingers and toes
- Digestive distress, nausea, loss of appetite, vomiting, constipation,
- Deposits in the cornea of the eye
- Heart failure
- Discoloration of the skin (a blue-grey tinge)
- Rash, skin reaction (requires immediate medical attention!)
- Pancreatitis, liver damage
- Blood disorders
But a scarier side effect or Amiodarone was revealed in the journal Cancer (online, April 8 2013), . In a study tracking 6,000 patients who received amiodarone, between 1997 and 2008. According to this study, for men who took amiodarone over at least a year, there was an elevated risk of cancer of 46%. And at the highest dose, the risk increased to 98%.
If you take amiodarone, at the first sign of any symptoms, contact the doctor who prescribed you immediately.
DO NOT STOP taking amiodarone suddenly by yourself. it might trigger life-threatening arrhythmias. Do it only under the careful supervision of the prescribing physician and in a gradual manner.
Other Cancer-Causing Medications
There are other prescribed medications that have shown to cause cancer, at least in animals but no one seems to know whether this constitutes a problem for people and they are manufactured, prescribed and taken every day:
OMEPRAZOLE (Prilosec), a medication prescribed for heartburn or reflux. The drug causes abnormal cell growth and stomach tumors in rats.
SPIRONOLACTONE (Aldactazide, Aldactone) a blood pressure medicine also prescribed for hormonal imbalances and facial hair growth in women. It also causes tumors in rats.
ELIDEL cream and Protopic ointment. Prescriptions for topical skin treatments, for children with eczema cause worries by reports that the medicines are associated with lymphoma and skin cancer. And there is a FDA warning against using these drugs in children under two years of age, stating that, “The long term safety of Elidel and Protopic are unknown.”
CIMZIA, ENBREL, HUMIRA and REMICADE The very expensive rheumatoid arthritis injections raise the same worries. These are bio-tech drugs that have revolutionized the treatment of rheumatoid arthritis and Crohn’s disease. The FDA announced that it was investigating an association between these medications and the development of lymphoma or other cancers.
LIPITOR, MEVACOR, PRAVACHOL. Another very old controversial cancer connection has to do with cholesterol-lowering drugs. An article in the Journal of the American Medical Association (Jan. 3, 1996) warned that, “All members of the two most popular classes of lipid-lowering drugs (the fibrates and the statins) cause cancer in rodents, in some cases at levels of animal exposure close to those prescribed to humans.”
It is well known that statin drugs produce significant suppression of vital immune cells, the helper T-cells fundamental for protecting against cancer and fungal, bacterial and viral infections. Chronic immune suppression in the millions of patients taking statin drugs would mean that a very high number of them would be at high risk of developing cancer, and those already having cancer would see exponential growth and spread of their cancers.
Statins Also Linked to Breast Cancer
It has been known for some time that a high cholesterol levels reduces the risk of brest as well as most cancers. Lowering cholesterol levels increases the risk of breast cancer and of other types of cancers as well.
A large cholesterol study called the CARE study, in 1996 comparing women taking a statin drug to those not on a statin, found that 12 of 290 women in the statin group developed breast cancer compared to just 1 of 290 of the women not on the drug.
Since then, several studies have found the same link low cholesterol-higher breast cancer risk. and another study demonstrated a twofold increase in breast cancer in women taking a statin for at least 10 years.
BYETTA, JANUVIA, ONGLYZA and VICTOZA. Diabetes Drugs. Just recently the FDA has reported that these popular diabetes drugs have been recently linked to pancreatitis and pre-cancerous cellular changes in the pancreas.
Remicade (infliximab) is a TNF alpha-blocker medication used to treat serious auto-immune diseases such as ulcerative colitis, rheumatoid arthritis and severe psoriasis. The FDA warns that this and similar medications could lead to malignancies like lymphoma.
The TNF alpha-blocker are powerful medications which alleviate suffering from auto-immune disorders by dampening an overactive immune system. But an immune system that isn’t functioning properly may fail to detect infections, which can then rage out of control. Even more frightening, they may not be able to eliminate cancer.
Like Remicade, other TNF alpha-blocker drugs such as adalimumab (HUMIRA), certolizumab (CIMZIA), Golimimab (SYMPONY) are reported to cause lymphoma as a side effect.
BLOOD PRESSURE MEDICATIONS
According to the revised treatment protocols for hypertension by committee of experts:
- People over the age of 60 will no longer require medication unless their systolic (upper) blood pressure number exceeds 150.
- Beta-blockers like atenolol, metoprolol and propranolol are out as first-line therapies.
- ACE (angiotensin converting enzyme) inhibitors and ARBs (angiotensin receptor blockers) are the drugs now to be preferred for Hypertension treatment.
Popular ACE Inhibitor drugs:
- Benazepril (LOTENSIN)
- Captopril (CAPOTEN)
- Enalapril (VASOTEC)
- Lisinopril (PRINIVIL, ZESTRIL)
- Quinapril (ACCUPRIL)
- Ramipril (ALTACE)
ACEs Side Effects
While for the majority of patients are effective and do not cause side effects, some people experience a long list of side effects like:
- Dry cough, uncontrollable cough, nausea, vomiting
- Dizziness, excessively low blood pressure
- Kidney function changes, BUN & creatinine elevations
- Digestive distress, diarrhea, abdominal pain
- Tiredness, fatigue, malaise
- Excessive potassium levels (requires immediate medical attention!), irregular heart rhythms, chest pain
- Elevated uric acid levels
- Sensitivity to sunlight (photosensitivity), skin rash
- Angioedema (swelling of face, lips, tongue, throat)
- Angioedema (swelling in abdomen, severe abdominal pain)
- Severe allergic reaction (anaphylaxis) requiring emergency treatment
- Toxicity to liver or pancreas
- Blood disorders
- Potential birth defects if taken during early pregnancy
- Sexual difficulties
Of these, the dry cough, uncontrollable cough, could be the most typical side effect of ACE inhibitors.
Popular ARBS Inhibitor drugs
- Losartan (Cozaar)
- Olmesartan (Benicar)
- Telmisartan (Micardis)
- Valsartan (Diovan)
ARB Side Effects:
ARBs are less likely to cause uncontrollable cough but they too can trigger symptoms in susceptible people. Here are some side effects you have to be aware of:
- Dizziness, fatigue, low blood pressure
- Upper respiratory tract infections, sinusitis, stuffy nose,
- Digestive discomfort, diarrhea, stomach pain, back pain
- Joint pain, arthritis
- Swelling of the face, lips, mouth, tongue or throat (Requires immediate emergency medical treatment )
- Potassium retention and buildup (hyperkalemia)
- Kidney damage, liver damage
- Hair loss
NSAIDs (Non-Steroidal Anti-Inflammatory drugs)
Can OTC NSAIDs such as IBUPROFEN and NAPROXEN be DEADLY Pain Relievers?
Most people assume that because they are called non-prescription drugs, these drugs are super safe, and do not cause any side effects.
In fact, OTC drugs don’t carry such frightening alerts as they come with prescription drugs, and besides, we assume that the FDA is not supposed to allow any drug that has “toxicity” or the “potentiality for harmful effect” to be sold without prescription (Amendment to the Food, Drug, and Cosmetic Act, 1951).
So perhaps it is for this reasons that consumers believe OTC are perfectly safe. And perhaps the FDA do not consider death a harmful effect.
But what risks can OTC NSAIDs carry?
Gastrointestinal Side Effects
Though gastroenterologists worried about life-threatening complications such as bleeding or perforated ulcers, when ibuprofen (Advil, Motrin IB) was first allowed over the counter in 1984, the FDA decided that the overall benefits outweighed these concerns and went on to approve OTC status for naproxen (ALEVE).
Cardiovascular Side Effects
NSAIDs in general (including drugs such as diclofenac, meloxicam and piroxicam as well as ibuprofen and naproxen) are linked to a higher risk of heart attack, stroke and death from cardiovascular causes (JAMA, Oct. 4, 2006) http://www.ncbi.nlm.nih.gov/pubmed/1696883
Blood Clots in Veins
Now researchers have discovered that NSAIDs also increase the risk of blood clots in the veins, a serious complication that can lead to life threatening blood clots in the lungs (Rheumatology, Sept. 24, 2014).
A New Admission By FDA About NSAIDs
I bet: You or someone of your family make regular use of pain relievers products (Aleve, Celebrex, Advil, Adviltime, Daypro, and Naprosyn) also called NSAIDs (Non-Steroidal-Anti-inflamatory-Drugs) so please listen carefully to this:
the FDA is admitting now that your life is in danger!
The FDA is now requiring manufacturers of non-aspirin products, the NSAIDs, to clearly disclose their heart attack and stroke risks on the packaging of these common painkillers.
The new labels must expose the following warning: “The risk of heart attack or stroke can occur as early as the first weeks of using an NSAID. The risk may increase with longer use of the NSAID. The risk appears greater at higher doses.”
The FDA also requested that the labels must indicate that the risk doesn’t only apply to patients with heart disease, yet patients with heart disease are at a higher risk.
Obviously Big Pharma reacted immediately and the company Pfizer which manufactures Celebrex and Adviltime released a statement that said basically: It’s not our fault at all! It’s only people’s fault if they are so dumb to misuse our products! Hopefully with this labeling we can now help them not be so dumb!
But it has been known for a while how these drugs are NOT safe, there are studies that show their risk of heart attack, stroke, and sudden death. And it doesn’t take years of taking them to see their side effects. It’s disgusting that drug companies are still willing to risk people’s health in order to defend their killer products. They unscrupulously continue to release statements about how “safe” their products are.
And it is disgraceful that is has taken more than one year for the FDA to act since they first looked at the reports back in February of 2014. Meanwhile, how many people died–either partially or wholly–due to side effects of these drugs in that span of time?
How FDA fixed The Problem
Now, a warning label is a good thing, but it’s just that—a warning label, Not a law, and a warning is especially ineffective in the prescription form, since irresponsible doctors are allowed to continue to prescribe this stuff.
So time will pass, and everyone will forget the FDA warning, and people will keep taking them saying “Oh, it must be OK—my God-doctor prescribed it.
So, in case you still have this stuff in your medicine cabinet, I would advise that You get rid of it right away.
The Most Dangerous OTC drug
And remember, ANY drug is just as bad or worse than NSAIDS, take Tylenol, for instance: it is the most dangerous drug -unfortunately ubiquitous in every medicine cabinet, and the leading cause of liver failure in the United States (not to mention cirrhosis and chronic liver disease).
A Deadly Combination: NSAIDs and Antidepressants
Another study has just come out, revealing an even more frightening danger linked to NSAIDs.
According to this latest research, the combination of antidepressants and NSAIDs increases the risk for intracranial haemorrhage regardless of the type of NSAID or antidepressant.
So besides bleeding ulcers and heart attacks now you have to worry about bleeding in the brain!
This is really quite a serious problem, because 65% of adults with major depression also have chronic pain, so it’s common for doctors to prescribe NSAIDs and antidepressants together to people. And these people have no idea of the risk they are taking.
It’s well known documented that even taken separately, both antidepressants and NSAIDs cause an increased risk for gastrointestinal bleeding. But neither one has ever been linked with an increased risk for intracranial hemorrhage before. Now these new studies show that when these two drugs are combined, the risk of inter-cranial hemorrhage increased 1.5 times. And it could happen within 30 days of combining the two medications.
Men had more than double the risk than women did.
Overmedication Within The Top Ten Leading Causes Of Death.
So if you are still stuck to your poisonous medicines, consider that over-medicating is one of the top-10 leading causes of death in the Western countries, and at least start asking yourself how safe is it to be combining certain medications and, even better, ask yourself if it is really necessary to be taking everything you’re prescribed.
The fact is, most problems now you are trying (in vain) to solve with NSAIDs or anti-depressants can be treated with nutritional natural supplements. And I know that these natural therapies certainly do not cause any risk for intracranial bleeding!
ANTICHOLINERGICS (AC) And Your Brain
Can Anticholinergics Be Bad For Your Brain?
Anticholinergics are a class of drugs that are used to treat diseases like asthma, incontinence, gastrointestinal cramps, and muscular spasms, they do so by blocking the action of the neurotransmitter acetylcholine in the brain
They are also prescribed for depression and sleep disorders. The drugs help to block involuntary movements of the muscles associated with these diseases.
Most anticholinergics are only available with a doctor’s prescription. Some examples include:
- Trihexyphenidyl (ARTANE)
- Benztropine mesylate (COGENTIN)
- 2,5 antihistamines (ORPHENADRINE)
- Flavoxate (URISPAS)
- Oxybutynin (DITROPAN, OXYTROL)
- Hyoscyamine (LEVISINEX)
- Tolterodine (DETROL)
- Belladonna alkaloids
- Fesoterodine (TOVIAZ)
- Solifenacin (VESIcare)
- Darifenacin (ENABLEX)
- Propantheline (Pro-Banthine) (UCSF)
Neuroscientists have been concerned for years that anticholinergic drugs (AC) could be bad for your brain because they interfere with a neurochemical called acetylcholine and alter brain cell function.
In fact, a new research (JAMA Neurology, online, April 18, 2016) confirms that:
“The use of AC medication was associated with increased brain atrophy and dysfunction and clinical decline. Thus, use of AC medication among older adults should likely be discouraged if alternative therapies are available.”
The study involved 451 older people who were considered “cognitively normal” at the start of the research, who were tested for their memory and mental functioning over the course of the trial. Some were given PET scans while others got MRI technology scans to determine the size and shape of their brains.
Here is what the investigators found, in their own words:
“Use of medications with medium or high AC effects in the ADNI cohort was associated with poorer cognition (particularly in immediate memory recall and executive function), reduced glucose metabolism, whole-brain and temporal lobe atrophy, and clinical decline. The effect appeared additive because an increased burden of AC medications was associated with poorer executive function and increased brain atrophy. Similar effects were seen in an independent cohort of older adults. These results suggest that medications with AC properties may be detrimental to brain structure and function, as well as cognition.”
In other words, drugs with anticholinergic activity are bad for your brain. The more medicines you take with AC action, the worse the impact.
Unfortunately, there dozens of over-the-counter drugs with AC activity:
antihistamines such as brompheniramine and diphenhydramine are considered anticholinergic medications. And all the nighttime pain relievers, Advil, Aleve, Bayer, Excedrin and Tylenol
So We Are At The Point Where We Should Ask Ourselves
Is the FDA Protecting Drug Companies or Patients?
Is the FDA protecting the public adequately? Why won’t the agency release generic drug information so we can all see whether these drugs are really equal?
It looks as if the FDA focuses resources just on approving drugs as quickly as possible, and its decision process are not nearly as transparent as the public would like.
An expose’ in the journal JAMA Internal Medicine (online, Feb. 9, 2015) found that when the FDA discovers research misconduct in clinical trials, it does not let the public know the details.
According to investigative journalist Charles Seife “the FDA has shown a pattern of burying the details of misconduct.”
Charles Seife, explained in a Slate Essay:
“When the FDA finds scientific fraud or misconduct, the agency doesn’t notify the public, the medical establishment, or even the scientific community that the results of a medical experiment are not to be trusted” (Slate, Feb. 8, 2015).
The FDA’s documents are frequently redacted. Even when they are available, information on the drug, the study site or the pharmaceutical company involved may be blacked out, making it difficult to trace which drug was involved”.
Until next time.